Marvel’s Animation panel at NYCC revealed that the Guardians of the Galaxy (who will be getting their own animated show in the near future) will be guest staring in an episode of The Incredible Hulk and the Agents of S.M.A.S.H. See the description from Jeph Loeb below:
The episode begins with Hulk’s team lost in space, though Red Hulk points out that “Thanks to the Leader, everyone on Earth thinks we’re criminals — they don’t want us to come home.” They’re soon invited to meet the Avengers on a strange planet, but are promptly placed under arrest by Cap’s crew. A battle ensues. Just as things are calming down, the Guardians arrive.